The purpose of this study was to analyze the effects of music activities on negative emotion regulation of adolescents. A meta-analysis was conducted on master’s and doctoral theses and journals published in Korea until September 2020. From 39 studies, 81 effect size were extracted and the overall average effect size was large effect size. As a result, music activities was found to be very effective way on negative emotion regulation of adolescents. The effect size in characteristics of the subjects difference follows: In relation to gender, mixed, women and men were in order, and the age, mixed, high grade, middle grade were in order. Also, the types were general, facility residence, maladjustment, other, athlete and player were in order. As regards the intervention methods, active and mixed showed a large effect size, and the receptive showed a medium effect size. A close look at the intervention characteristics revealed that the effect size was the most effective when 9~16 sessions were carried out and it lasts 40~60 minutes per session. The last, non-music therapists were higher than music therapists, but there was no statistically significant difference. This results of this study showed that music activities can have a positive effect on negative emotion regulation of adolescents.